Genetic variation of CYP2A6, smoking, and risk of cancer

Lancet. 1999 Mar 13;353(9156):898-9. doi: 10.1016/S0140-6736(98)04984-8.
No abstract available

Publication types

  • Letter
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Alleles
  • Aryl Hydrocarbon Hydroxylases*
  • Case-Control Studies
  • Cytochrome P-450 CYP2A6
  • Cytochrome P-450 Enzyme System / deficiency
  • Cytochrome P-450 Enzyme System / genetics*
  • Genotype
  • Humans
  • Los Angeles
  • Lung Neoplasms / etiology
  • Lung Neoplasms / genetics*
  • Mixed Function Oxygenases / deficiency
  • Mixed Function Oxygenases / genetics*
  • Nicotine / metabolism
  • Risk Factors
  • Smoking / adverse effects
  • Smoking / genetics*
  • Smoking / metabolism

Substances

  • Nicotine
  • Cytochrome P-450 Enzyme System
  • Mixed Function Oxygenases
  • Aryl Hydrocarbon Hydroxylases
  • CYP2A6 protein, human
  • Cytochrome P-450 CYP2A6