Conjugated polysaccharide vaccines

Infect Dis Clin North Am. 1999 Mar;13(1):113-33, vii. doi: 10.1016/s0891-5520(05)70046-5.

Abstract

The joining of polysaccharide antigens to various proteins can result in increased immunogenicity of vaccines composed of such antigens. This article discusses conjugated polysaccharide vaccines for Haemophilus influenzae, Streptococcus pneumoniae, and Neisseria meningitis. Increased availability and use of such vaccines may result in the ability to give more effective vaccines earlier in life, further reducing the incidence of diseases caused by these organisms.

Publication types

  • Review

MeSH terms

  • Adult
  • Animals
  • Bacterial Vaccines / administration & dosage
  • Bacterial Vaccines / adverse effects
  • Bacterial Vaccines / immunology*
  • Child
  • Child, Preschool
  • Haemophilus influenzae / immunology
  • Humans
  • Infant
  • Neisseria meningitidis / immunology
  • Polysaccharides, Bacterial / immunology*
  • Streptococcus pneumoniae / immunology
  • Vaccines, Conjugate / administration & dosage
  • Vaccines, Conjugate / adverse effects
  • Vaccines, Conjugate / immunology*

Substances

  • Bacterial Vaccines
  • Polysaccharides, Bacterial
  • Vaccines, Conjugate