Abstract
Genomic DNA encoding for human aldehyde reductase (AKR1A1), a member of the aldo-keto reductase superfamily, was isolated and characterized. The genomic DNA is approximately 16 kb in length and contains eight exons which encode the entire coding region and the 3'-untranslated sequences. AKR1A1 was localized on chromosome 1p33-->p32 by fluorescence in situ hybridization.
Publication types
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Comparative Study
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Research Support, Non-U.S. Gov't
MeSH terms
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3' Untranslated Regions / genetics
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Aldehyde Reductase / genetics*
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Animals
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Chromosomes, Human, Pair 1 / genetics*
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Cloning, Molecular
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Exons / genetics
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Genomic Library
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Humans
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In Situ Hybridization, Fluorescence
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Introns / genetics
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Molecular Sequence Data
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Physical Chromosome Mapping*
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Rats
Substances
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3' Untranslated Regions
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AKR1A1 protein, human
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Aldehyde Reductase
Associated data
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GENBANK/AF036680
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GENBANK/AF036681
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GENBANK/AF036682
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GENBANK/AF036683
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GENBANK/AH005744