The structural organization of the human aldehyde reductase gene, AKR1A1, and mapping to chromosome 1p33-->p32

Cytogenet Cell Genet. 1999;84(3-4):230-2. doi: 10.1159/000015265.

Abstract

Genomic DNA encoding for human aldehyde reductase (AKR1A1), a member of the aldo-keto reductase superfamily, was isolated and characterized. The genomic DNA is approximately 16 kb in length and contains eight exons which encode the entire coding region and the 3'-untranslated sequences. AKR1A1 was localized on chromosome 1p33-->p32 by fluorescence in situ hybridization.

Publication types

  • Comparative Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • 3' Untranslated Regions / genetics
  • Aldehyde Reductase / genetics*
  • Animals
  • Chromosomes, Human, Pair 1 / genetics*
  • Cloning, Molecular
  • Exons / genetics
  • Genomic Library
  • Humans
  • In Situ Hybridization, Fluorescence
  • Introns / genetics
  • Molecular Sequence Data
  • Physical Chromosome Mapping*
  • Rats

Substances

  • 3' Untranslated Regions
  • AKR1A1 protein, human
  • Aldehyde Reductase

Associated data

  • GENBANK/AF036680
  • GENBANK/AF036681
  • GENBANK/AF036682
  • GENBANK/AF036683
  • GENBANK/AH005744