High levels of yessotoxin in mussels and presence of yessotoxin and homoyessotoxin in dinoflagellates of the Adriatic Sea

Toxicon. 1999 Aug;37(8):1187-93. doi: 10.1016/s0041-0101(98)00254-2.

Abstract

Identification of YTX and homoYTX in natural phytoplankton populations containing significant amounts of Gonyaulax polyedra and determination of detailed toxin profiles of mussels (Mytilus galloprovincialis) periodically collected from two sites of the Northern Adriatic coast from February to October 1997 was performed by LC-FLD following derivatization with ADAM or DMEQ-TAD and LC-MS and LC-MS-MS. OA and YTX concentrations were recorded in the range 0.11-2.31 and 0.18-9.02 microg per g of hepatopancreas, respectively. HomoYTX was also detected both in phytoplankton and mussel samples.

MeSH terms

  • Animals
  • Bivalvia / chemistry*
  • Digestive System / chemistry
  • Dinoflagellida / chemistry*
  • Ethers, Cyclic / isolation & purification*
  • Fluorometry
  • Italy
  • Mice
  • Mollusk Venoms
  • Oxocins*
  • Phytoplankton / chemistry*
  • Saxitoxin / isolation & purification*
  • Survival Rate

Substances

  • Ethers, Cyclic
  • Mollusk Venoms
  • Oxocins
  • Saxitoxin
  • yessotoxin