Haemochromatosis gene C282Y homozygotes in an elderly male population

Lancet. 1999 Jul 17;354(9174):221-2. doi: 10.1016/S0140-6736(99)02195-9.

Abstract

We found that C282Y homozygosity was not under-represented in an elderly male population. This suggests that life-threatening, haemochromatosis-related disease may not occur in many C282Y homozygotes.

Publication types

  • Letter

MeSH terms

  • Aged
  • Aged, 80 and over
  • Alanine Transaminase / blood
  • Alkaline Phosphatase / blood
  • Bilirubin / blood
  • Blood Glucose / analysis
  • HLA Antigens / genetics*
  • Hemochromatosis / blood
  • Hemochromatosis / genetics*
  • Hemochromatosis Protein
  • Histocompatibility Antigens Class I / genetics*
  • Homozygote
  • Humans
  • Male
  • Membrane Proteins*
  • Mutation
  • Polymerase Chain Reaction

Substances

  • Blood Glucose
  • HFE protein, human
  • HLA Antigens
  • Hemochromatosis Protein
  • Histocompatibility Antigens Class I
  • Membrane Proteins
  • Alanine Transaminase
  • Alkaline Phosphatase
  • Bilirubin