The DNA repair gene MBD4 (MED1) is mutated in human carcinomas with microsatellite instability

Nat Genet. 1999 Nov;23(3):266-8. doi: 10.1038/15443.
No abstract available

Publication types

  • Letter
  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • DNA Mutational Analysis
  • DNA Repair / genetics*
  • Endodeoxyribonucleases / genetics*
  • Endodeoxyribonucleases / physiology*
  • Gene Frequency
  • Humans
  • Loss of Heterozygosity
  • Microsatellite Repeats / genetics
  • Mutation*
  • Neoplasms / enzymology
  • Neoplasms / genetics*
  • Neoplasms / pathology
  • Polymorphism, Single-Stranded Conformational
  • Trinucleotide Repeat Expansion / genetics*

Substances

  • Endodeoxyribonucleases
  • MBD4 protein, human