1H MRS detects polyunsaturated fatty acid accumulation during gene therapy of glioma: implications for the in vivo detection of apoptosis

Nat Med. 1999 Nov;5(11):1323-7. doi: 10.1038/15279.
No abstract available

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Apoptosis* / drug effects
  • Brain Neoplasms / metabolism
  • Brain Neoplasms / pathology
  • Brain Neoplasms / therapy*
  • Brain Neoplasms / ultrastructure
  • Fatty Acids, Unsaturated / metabolism*
  • Ganciclovir / pharmacology
  • Ganciclovir / therapeutic use
  • Genetic Therapy*
  • Glioma / metabolism
  • Glioma / pathology
  • Glioma / therapy*
  • Glioma / ultrastructure
  • Humans
  • Magnetic Resonance Spectroscopy / methods*
  • Microscopy, Electron
  • Protons

Substances

  • Fatty Acids, Unsaturated
  • Protons
  • Ganciclovir