Abstract
The formation of the root epidermis of Arabidopsis provides a simple and elegant model for the analysis of cell patterning. A novel gene, WEREWOLF (WER), is described here that is required for position-dependent patterning of the epidermal cell types. The WER gene encodes a MYB-type protein and is preferentially expressed within cells destined to adopt the non-hair fate. Furthermore, WER is shown to regulate the position-dependent expression of the GLABRA2 homeobox gene, to interact with a bHLH protein, and to act in opposition to the CAPRICE MYB. These results suggest a simple model to explain the specification of the two root epidermal cell types, and they provide insight into the molecular mechanisms used to control cell patterning.
Publication types
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Comparative Study
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Research Support, Non-U.S. Gov't
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Research Support, U.S. Gov't, Non-P.H.S.
MeSH terms
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Amino Acid Sequence
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Arabidopsis / genetics
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Arabidopsis / growth & development*
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Arabidopsis Proteins*
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Cell Lineage
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Cloning, Molecular
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DNA-Binding Proteins / genetics*
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Gene Expression Regulation, Plant
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Genes, Homeobox
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Genes, Plant*
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Genes, Regulator
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Homeodomain Proteins / biosynthesis
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Hypocotyl / genetics
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Hypocotyl / growth & development*
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Models, Biological
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Molecular Sequence Data
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Plant Proteins / biosynthesis
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Plant Proteins / genetics*
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Plant Roots / genetics
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Plant Roots / growth & development*
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Proto-Oncogene Proteins c-myb*
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Sequence Homology, Amino Acid
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Tissue Distribution
Substances
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ATR1 protein, Arabidopsis
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Arabidopsis Proteins
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CPC protein, Arabidopsis
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DNA-Binding Proteins
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GL2 protein, Arabidopsis
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Homeodomain Proteins
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Plant Proteins
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Proto-Oncogene Proteins c-myb
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WER protein, Arabidopsis