Selfish operons: the evolutionary impact of gene clustering in prokaryotes and eukaryotes

Curr Opin Genet Dev. 1999 Dec;9(6):642-8. doi: 10.1016/s0959-437x(99)00025-8.

Abstract

The Selfish Operon Model postulates that the organization of bacterial genes into operons is beneficial to the constituent genes in that proximity allows horizontal cotransfer of all genes required for a selectable phenotype; eukaryotic operons formed for very different reasons. Horizontal transfer of selfish operons most probably promotes bacterial diversification.

Publication types

  • Comparative Study
  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Animals
  • Bacteria / genetics*
  • Caenorhabditis elegans / genetics*
  • Eukaryotic Cells
  • Evolution, Molecular*
  • Genes*
  • Genes, Bacterial / genetics
  • Models, Genetic*
  • Operon / genetics*
  • Selection, Genetic