Chromium (III) is one of the trace elements, which are necessary for human and animal vital activity. It enters the organism from digestive tract and is transported to the tissues, where its accumulation takes place. The deficiency of chromium (III) causes the disturbances in metabolic processes. The primary reaction of organism on chromium (III) deficiency, is the lowered tolerance of glucose, which is the consequence of changes in insulin affinity to its receptors on cells. The considerable quantities of chromium (III) reveal in nucleic acids. It influences on their metabolism, replication and transcription. The ion decreases the content of corticosteroids in plasma and increases the functional activity of immune system of organism.