Abstract
We report a case of acute hepatitis B after autologous stem cell transplantation (ASCT) in a patient with low-grade non-Hodgkin's lymphoma. At diagnosis of the hematological disease, the patient had the characteristic serology of a previous hepatitis B infection, being Ag HBs negative, hepatitis B virus core antibody positive (anti-HBC) and hepatitis B virus surface antibody weakly positive. He developed fatal hepatitis B after autologous stem cell transplantation, suggesting reactivation consequent to immunosuppression.
MeSH terms
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Acute Disease
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Antineoplastic Combined Chemotherapy Protocols / adverse effects
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Hematopoietic Stem Cell Transplantation / adverse effects*
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Hepatitis B / etiology*
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Hepatitis B / transmission
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Hepatitis B Antibodies / blood
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Hepatitis B Antigens / blood
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Hepatitis B virus / isolation & purification
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Humans
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Immunosuppression Therapy / adverse effects
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Lymphoma, Non-Hodgkin / therapy
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Lymphoma, Non-Hodgkin / virology
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Male
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Middle Aged
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Transplantation, Autologous / adverse effects
Substances
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Hepatitis B Antibodies
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Hepatitis B Antigens