The human SOX18 gene: cDNA cloning and high resolution mapping

S Stanojcić; M Stevanović

doi:10.1016/s0167-4781(00)00078-6

The human SOX18 gene: cDNA cloning and high resolution mapping

Biochim Biophys Acta. 2000 Jun 21;1492(1):237-41. doi: 10.1016/s0167-4781(00)00078-6.

Authors

S Stanojcić¹, M Stevanović

Affiliation

¹ Institute of Molecular Genetics and Genetic Engineering, Vojvode Stepe 444a, PO Box 794, 11001 Belgrade, Yugoslavia.

PMID: 10858556
DOI: 10.1016/s0167-4781(00)00078-6

Abstract

SOX genes comprise a family of genes that are related to the mammalian sex determining gene SRY and these genes play key roles during animal development. We report here cloning and characterisation of the human SOX18 gene. SOX18 gene is expressed in foetal brain as well as in a wide range of foetal and adult tissues indicating its function is not restricted to early development. Mapping analysis has revealed that SOX18 gene is located on human chromosome 20q13.3, 27.29 cR distal from the marker D20S173.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Amino Acid Sequence
Central Nervous System / physiology
Chromosome Mapping
Chromosomes, Human, Pair 20*
Cloning, Molecular
DNA, Complementary / analysis
Fetus / physiology
High Mobility Group Proteins / genetics*
Humans
Molecular Sequence Data
SOXF Transcription Factors
Sequence Homology, Amino Acid
Transcription Factors / genetics*

Substances

DNA, Complementary
High Mobility Group Proteins
SOX18 protein, human
SOXF Transcription Factors
Transcription Factors

Associated data

GENBANK/AJ243896