Abstract
Interferon-beta (IFN-beta) is administered for treatment of multiple sclerosis (MS). We report on a woman with MS who presented with severe Raynaud's phenomenon, livedo-reticularis and digital necrosis two weeks after beginning therapy with IFN-beta. Symptoms improved after the IFN-beta was discontinued and anticoagulation associated with cyclophosphamide and corticoid were introduced. Raynaud's phenomenon is probably a side effect of IFN-beta therapy for multiple sclerosis.
Publication types
-
Case Reports
-
English Abstract
MeSH terms
-
Adjuvants, Immunologic / adverse effects*
-
Adjuvants, Immunologic / therapeutic use
-
Anticoagulants / therapeutic use
-
Drug Therapy, Combination
-
Female
-
Fingers / pathology
-
Glucocorticoids / therapeutic use
-
Humans
-
Immunosuppressive Agents / therapeutic use
-
Interferon-beta / adverse effects*
-
Interferon-beta / therapeutic use
-
Middle Aged
-
Multiple Sclerosis / drug therapy*
-
Necrosis
-
Raynaud Disease / chemically induced*
-
Raynaud Disease / drug therapy
-
Raynaud Disease / pathology
-
Skin Diseases, Vascular / chemically induced
-
Skin Diseases, Vascular / drug therapy
-
Skin Diseases, Vascular / pathology
Substances
-
Adjuvants, Immunologic
-
Anticoagulants
-
Glucocorticoids
-
Immunosuppressive Agents
-
Interferon-beta