Cytotoxins directed at interleukin-4 receptors as therapy for human brain tumors

MeSH terms

• ADP Ribose Transferases*
• Animals
• Antineoplastic Agents / chemistry
• Antineoplastic Agents / pharmacology
• Antineoplastic Agents / therapeutic use*
• Bacterial Toxins*
• Brain Neoplasms / drug therapy*
• Brain Neoplasms / metabolism
• Brain Neoplasms / pathology
• Clinical Trials, Phase I as Topic
• Exotoxins / therapeutic use*
• Glioblastoma / drug therapy
• Glioblastoma / metabolism
• Glioblastoma / pathology
• Glioma / drug therapy*
• Glioma / metabolism
• Glioma / pathology
• Guinea Pigs
• Humans
• Immunotoxins / administration & dosage
• Immunotoxins / pharmacology
• Immunotoxins / therapeutic use*
• Injections, Intralesional
• Injections, Intraperitoneal
• Injections, Intravenous
• Injections, Spinal
• Interleukin-4 / physiology*
• Macaca fascicularis
• Mice
• Mice, Nude
• Neoplasm Proteins / chemistry
• Neoplasm Proteins / drug effects*
• Neuroblastoma / drug therapy
• Neuroblastoma / metabolism
• Neuroblastoma / pathology
• Protein Structure, Tertiary
• Pseudomonas aeruginosa Exotoxin A
• Rats
• Receptors, Interleukin-4 / chemistry
• Receptors, Interleukin-4 / drug effects*
• Treatment Outcome
• Tumor Stem Cell Assay
• Virulence Factors*
• Xenograft Model Antitumor Assays