Contrasting roles of IL-2 and IL-15 in the life and death of lymphocytes: implications for immunotherapy

Immunity. 2001 Feb;14(2):105-10.

Authors

T A Waldmann¹, S Dubois, Y Tagaya

Affiliation

¹ Metabolism Branch, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, USA. tawald@helix.nih.gov

PMID: 11239443

No abstract available

Publication types

Review

MeSH terms

Animals
Antibodies, Monoclonal / therapeutic use
Apoptosis
Autoimmune Diseases / therapy
CD8-Positive T-Lymphocytes / cytology
CD8-Positive T-Lymphocytes / immunology
Cancer Vaccines / therapeutic use
Graft Rejection / prevention & control
Humans
Immunologic Memory
Immunotherapy / methods*
Interleukin-15 / antagonists & inhibitors
Interleukin-15 / physiology*
Interleukin-2 / antagonists & inhibitors
Interleukin-2 / physiology*
Leukemia / therapy
Lymphocyte Activation
Lymphocytes / cytology*
Lymphocytes / immunology*
Lymphoma / therapy
Mice
Models, Biological
Neoplasms / therapy

Substances

Antibodies, Monoclonal
Cancer Vaccines
Interleukin-15
Interleukin-2