Abstract
Different subsets of dendritic cells (DCs) appear to play a role in determining the specific cytokines secreted by T helper (Th) cells. A model is proposed that links together factors such as the pathogen, microenvironment, DCs and T cells in a mechanism that results in a flexible determination of T-cell polarization.
Publication types
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Research Support, Non-U.S. Gov't
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Research Support, U.S. Gov't, P.H.S.
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Review
MeSH terms
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Adjuvants, Immunologic / physiology*
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Animals
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Cell Differentiation / immunology
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Cell Lineage / immunology
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Dendritic Cells / classification
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Dendritic Cells / cytology
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Dendritic Cells / immunology*
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Growth Substances / immunology*
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Humans
Substances
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Adjuvants, Immunologic
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Growth Substances