Induction of HIF-1alpha in response to hypoxia is instantaneous

FASEB J. 2001 May;15(7):1312-4.

Authors

U R Jewell¹, I Kvietikova, A Scheid, C Bauer, R H Wenger, M Gassmann

Affiliation

¹ Institute of Physiology, University of Zürich, CH-8057 Zürich, Switzerland.

PMID: 11344124

No abstract available

MeSH terms

Carbon-Oxygen Lyases / metabolism
Cell Hypoxia / physiology*
DNA-(Apurinic or Apyrimidinic Site) Lyase*
DNA-Binding Proteins / genetics
DNA-Binding Proteins / metabolism*
Gene Expression Regulation*
HeLa Cells
Humans
Hypoxia-Inducible Factor 1
Hypoxia-Inducible Factor 1, alpha Subunit
Immunoblotting
Kinetics
NF-kappa B / metabolism
Nuclear Proteins / genetics
Nuclear Proteins / metabolism*
Oxygen / metabolism*
Proto-Oncogene Proteins c-fos / metabolism
Proto-Oncogene Proteins c-jun / metabolism
Thioredoxins / metabolism
Time Factors
Transcription Factors / genetics
Transcription Factors / metabolism*

Substances

DNA-Binding Proteins
HIF1A protein, human
Hypoxia-Inducible Factor 1
Hypoxia-Inducible Factor 1, alpha Subunit
NF-kappa B
Nuclear Proteins
Proto-Oncogene Proteins c-fos
Proto-Oncogene Proteins c-jun
Transcription Factors
Thioredoxins
Carbon-Oxygen Lyases
APEX1 protein, human
DNA-(Apurinic or Apyrimidinic Site) Lyase
Oxygen