The impact of norfloxacin, ciprofloxacin and ofloxacin on human gut colonization by Candida albicans

E Mavromanolakis; S Maraki; A Cranidis; Y Tselentis; D P Kontoyiannis; G Samonis

doi:10.1080/00365540152030006

The impact of norfloxacin, ciprofloxacin and ofloxacin on human gut colonization by Candida albicans

Scand J Infect Dis. 2001;33(6):477-8. doi: 10.1080/00365540152030006.

Authors

E Mavromanolakis¹, S Maraki, A Cranidis, Y Tselentis, D P Kontoyiannis, G Samonis

Affiliation

¹ Department of Urology, University Hospital of Iráklion, Crete, Greece.

PMID: 11450873
DOI: 10.1080/00365540152030006

Abstract

We studied gastrointestinal (GI) colonization by Candida albicans in patients receiving oral norfloxacin, ciprofloxacin or ofloxacin as monotherapy for urinary tract infections. Quantitative stool cultures for C. albicans were performed before, at the end and 1 week after the end of treatment. All 3 quinolones increased GI colonization by C. albicans. Ciprofloxacin caused the highest increase, which was not statistically significant.

MeSH terms

Adult
Aged
Anti-Infective Agents / adverse effects*
Anti-Infective Agents / therapeutic use
Candida albicans / drug effects*
Ciprofloxacin / adverse effects*
Ciprofloxacin / therapeutic use
Digestive System / drug effects
Digestive System / microbiology*
Female
Humans
Male
Middle Aged
Norfloxacin / adverse effects*
Norfloxacin / therapeutic use
Ofloxacin / adverse effects*
Ofloxacin / therapeutic use
Urinary Tract Infections / drug therapy

Substances

Anti-Infective Agents
Ciprofloxacin
Ofloxacin
Norfloxacin