The clinical profile of childhood optic neuritis

Arq Neuropsiquiatr. 2001 Jun;59(2-B):311-7. doi: 10.1590/s0004-282x2001000300001.

Abstract

Purpose: To report the clinical features and outcome of a series of children with optic neuritis.

Methods: We reviewed the medical records of patients up to 16 years old with optic neuritis. Group 1 comprised children seen up to two weeks after the onset of visual loss; Group 2 comprised patients already harboring optic atrophy.

Results: There were 15 boys and 12 girls. The mean age was 10.9 years. Bilateral optic neuritis occurred in 10. Optic disc pallor was found in 35%, edema in 46%, and 19% had normal fundus. During follow-up visual acuity improved in all but one eye in Group 1, and in six of seven eyes in children in Group 2. Just one child converted to multiple sclerosis.

Conclusions: This study shows that the clinical features of childhood optic neuritis differ from those observed in adults. In children it has a better visual outcome and a lower conversion rate to multiple sclerosis than in adults.

MeSH terms

  • Adolescent
  • Child
  • Child, Preschool
  • Female
  • Follow-Up Studies
  • Humans
  • Male
  • Multiple Sclerosis / etiology
  • Optic Neuritis / complications
  • Optic Neuritis / physiopathology*
  • Retrospective Studies
  • Visual Acuity / physiology