Evaluating the child with purpura

Am Fam Physician. 2001 Aug 1;64(3):419-28.

Abstract

Purpura is the result of hemorrhage into the skin or mucosal membrane. It may represent a relatively benign condition or herald the presence of a serious underlying disorder. Purpura may be secondary to thrombocytopenia, platelet dysfunction, coagulation factor deficiency or vascular defect. Investigation to confirm a diagnosis or to seek reassurance is important. Frequently, the diagnosis can be established on the basis of a careful history and physical examination, and a few key laboratory tests. Indicated tests include a complete blood cell count with platelet count, a peripheral blood smear, and prothrombin and activated partial thromboplastin times.

Publication types

  • Review

MeSH terms

  • Algorithms
  • Blood Coagulation
  • Blood Coagulation Disorders / diagnosis*
  • Blood Coagulation Disorders / physiopathology
  • Child
  • Diagnosis, Differential
  • Humans
  • IgA Vasculitis / diagnosis
  • Leukemia / complications
  • Leukemia / diagnosis
  • Lupus Erythematosus, Systemic / complications
  • Lupus Erythematosus, Systemic / diagnosis
  • Purpura / diagnosis*
  • Purpura / etiology*
  • Purpura, Thrombocytopenic, Idiopathic / diagnosis
  • Uremia / complications
  • Uremia / diagnosis