A CAN-induced cyclodimerization-Ritter trapping strategy for the one-pot synthesis of 1-amino-4-aryltetralins from styrenes

Vijay Nair; Roshini Rajan; Nigam P Rath

doi:10.1021/ol0257934

A CAN-induced cyclodimerization-Ritter trapping strategy for the one-pot synthesis of 1-amino-4-aryltetralins from styrenes

Org Lett. 2002 May 2;4(9):1575-7. doi: 10.1021/ol0257934.

Authors

Vijay Nair¹, Roshini Rajan, Nigam P Rath

Affiliation

¹ Organic Chemistry Division, Regional Research Laboratory (CSIR), Trivandrum, India. gvn@csrrltrd.ren.nic.in

PMID: 11975632
DOI: 10.1021/ol0257934

Abstract

[reaction: see text]. A facile one-pot synthesis of 1-amino-4-aryl-tetralin derivatives by the CAN-induced cyclodimerization of various styrenes in acetonitrile and acrylonitrile is described.