p53 codon 72 polymorphism in cervical cancer patients and healthy women from Poland

Acta Biochim Pol. 2000;47(4):1179-82.

Abstract

A polymorphism at codon 72 of gene p53 results in the presence of either arginine or proline at this position. We investigated the distribution of p53 codon 72 polymorphism in cervical cancer patients and a control group of healthy women from Poland. Our results do not confirm the hypothesis that the p53 codon polymorphism could play a role as a factor for squamous carcinoma of the cervix.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Carcinoma, Squamous Cell / genetics*
  • Codon*
  • Female
  • Genes, p53*
  • Genetic Predisposition to Disease
  • Humans
  • Papillomaviridae / genetics
  • Poland
  • Polymorphism, Genetic*
  • Uterine Cervical Neoplasms / genetics*

Substances

  • Codon