SIR2 family of NAD(+)-dependent protein deacetylases

Methods Enzymol. 2002:353:282-300. doi: 10.1016/s0076-6879(02)53056-1.

Authors

Jeffrey S Smith¹, Jose Avalos, Ivana Celic, Shabazz Muhammad, Cynthia Wolberger, Jef D Boeke

Affiliation

¹ Department of Biochemistry and Molecular Genetics, University of Virginia Health Sciences Center, Charlottesville, Virginia 22908, USA.

PMID: 12078503
DOI: 10.1016/s0076-6879(02)53056-1

No abstract available

MeSH terms

Acetylation
Amino Acid Sequence
Animals
Archaea / enzymology
Chickens
Cloning, Molecular
Gene Silencing
Histone Deacetylases / analysis
Histone Deacetylases / chemistry*
Histone Deacetylases / isolation & purification
Histone Deacetylases / metabolism*
Histones / metabolism
Humans
Models, Molecular
Molecular Sequence Data
Multigene Family
NAD / metabolism*
Protein Conformation
Sequence Homology, Amino Acid
Silent Information Regulator Proteins, Saccharomyces cerevisiae*
Sirtuin 1
Sirtuin 2
Sirtuins
Trans-Activators / analysis
Trans-Activators / chemistry*
Trans-Activators / isolation & purification
Trans-Activators / metabolism*

Substances

Histones
Silent Information Regulator Proteins, Saccharomyces cerevisiae
Trans-Activators
NAD
SIR2 protein, S cerevisiae
SIRT1 protein, human
Sirtuin 1
Sirtuin 2
Sirtuins
Histone Deacetylases