PIP: Uganda is experiencing a significant decline in the incidence of AIDS and it is one of the few developing countries where the AIDS epidemic shows signs of a turning point. The greatest declines are in the youngest age groups. Surveys indicate that an important reason for the declining incidence, particularly among young adults, is a change in sexual behavior. This article describes how the country, through the Uganda AIDS Commission (UAC), has successfully attacked the AIDS epidemic. The UAC is charged with containing the spread of the epidemic as well as finding a cure for the disease. Research monitoring is one of its programs. In addition, traditional healers have also been brought into the program and, through the organization Traditional Health and Modern Doctors Against AIDS, have developed herbal treatments against many opportunistic infections. A combination of a multisectoral approach and enormous political will to deal with the issue also plays a critical role in Uganda's success. Of particular relevance is the success of its aggressive AIDS education campaign, which is attributed to efforts of the government to increase awareness and promote condom use. A campaign to eliminate sexually transmitted diseases, which is also known to increase the risk of HIV transmission, is also underway.