A review of nerve agent exposure for the critical care physician

Crit Care Med. 2002 Oct;30(10):2346-54. doi: 10.1097/00003246-200210000-00026.

Abstract

Nerve agents are discussed. The article discusses their properties, routes of exposure, toxicodynamics, targets of toxicity, and treatment. It is concluded that a focused organized approach to the treatment of nerve agents is key to its successful management.

Publication types

  • Review

MeSH terms

  • Antidotes / therapeutic use
  • Chemical Warfare Agents* / chemistry
  • Chemical Warfare Agents* / poisoning
  • Cholinesterase Inhibitors / chemistry
  • Cholinesterase Inhibitors / poisoning
  • Decontamination / methods
  • Humans
  • Nervous System / drug effects
  • Organophosphate Poisoning
  • Organophosphates / chemistry
  • Organothiophosphorus Compounds / chemistry
  • Organothiophosphorus Compounds / poisoning
  • Sarin / chemistry
  • Sarin / poisoning
  • Soman / chemistry
  • Soman / poisoning

Substances

  • Antidotes
  • Chemical Warfare Agents
  • Cholinesterase Inhibitors
  • Organophosphates
  • Organothiophosphorus Compounds
  • Soman
  • VX
  • Sarin
  • tabun