Phylogenetic background and virulence profiles of fluoroquinolone-resistant clinical Escherichia coli isolates from the Netherlands

J Infect Dis. 2002 Dec 15;186(12):1852-6. doi: 10.1086/345767. Epub 2002 Nov 22.

Abstract

Thirteen fluoroquinolone-resistant Escherichia coli (FQREC) isolates from hospitalized patients in the Netherlands were found to represent predominantly (low-virulence) phylogenetic groups A and B1 and to lack extraintestinal virulence traits. These FQREC resemble animal-source E. coli and presumably pose little threat to noncompromised hosts. Similar analysis of other FQREC is needed.

Publication types

  • Comparative Study
  • Research Support, U.S. Gov't, Non-P.H.S.
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Anti-Infective Agents / pharmacology*
  • DNA, Bacterial / genetics
  • Drug Resistance, Bacterial
  • Escherichia coli / classification
  • Escherichia coli / drug effects*
  • Escherichia coli / pathogenicity
  • Escherichia coli Infections / epidemiology*
  • Escherichia coli Infections / microbiology
  • Fluoroquinolones
  • Genotype
  • Hospitals
  • Humans
  • Netherlands / epidemiology
  • Phylogeny
  • Virulence / genetics

Substances

  • Anti-Infective Agents
  • DNA, Bacterial
  • Fluoroquinolones