SV40 and human tumours: myth, association or causality?

Nat Rev Cancer. 2002 Dec;2(12):957-64. doi: 10.1038/nrc947.

Abstract

An increasing number of scientific reports have described evidence for a polyomavirus, simian virus 40, in a highly select group of human tumours. How did a simian virus infect humans and is the virus a passenger in tumours or is it important in their pathogenesis?

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, P.H.S.
  • Review

MeSH terms

  • Animals
  • Cell Transformation, Neoplastic
  • Disease Susceptibility
  • Genome, Viral
  • Humans
  • Mesothelioma / etiology
  • Mesothelioma / virology
  • Neoplasms / epidemiology
  • Neoplasms / etiology*
  • Neoplasms / pathology
  • Neoplasms / virology*
  • Simian virus 40 / genetics
  • Simian virus 40 / pathogenicity*
  • Simian virus 40 / physiology*