Both eyes of 74 healthy 2-12-month-old human infants were refracted twice with the new Welch Allyn SureSight non-cycloplegic autorefractor. At least one reliable estimate of sphere and cylinder was obtained from both eyes of all babies attempted, and 88% of infants contributed two estimates from each eye. These measurements were collected in less than 2 min. Although spherical estimates changed little over the first year (mean = +1.78 D), cylindrical error appeared to decrease from a mean of about 1.4 D (at 6 months) to 0.9 D (at 12 months). Refractive estimates and variability agreed well with published infant data obtained with traditional cycloplegic retinoscopy. Repeatability was excellent for measurement of cylinder but for sphere, 17% of infants' estimates differed by at least 1.0 D between tests. However, given its simplicity and time-efficiency, the SureSight should be a good candidate for the relatively easy screening of significant refractive error in non-verbal paediatric patients.