Abstract
This article describes a case of nodular fasciitis with the karyotype 47,XY,+4/46,XY,add(15)(p11.2), t(16;16)(p13.3;p11.2). The presence of clonal chromosomal abnormalities in this case, as well as in three previously reported cases, indicates that nodular fasciitis is a benign neoplasm and not a reactive lesion.
MeSH terms
-
Cell Transformation, Neoplastic
-
Chromosome Banding
-
Chromosomes, Human, Pair 15 / ultrastructure*
-
Chromosomes, Human, Pair 16 / ultrastructure*
-
Chromosomes, Human, Pair 3 / ultrastructure
-
Clone Cells / ultrastructure
-
Fasciitis / classification
-
Fasciitis / genetics
-
Fasciitis / pathology*
-
Fibroblasts / ultrastructure*
-
Hand Injuries / pathology
-
Humans
-
Karyotyping
-
Male
-
Middle Aged
-
Soft Tissue Neoplasms / classification
-
Soft Tissue Neoplasms / genetics
-
Soft Tissue Neoplasms / pathology*
-
Wound Healing