Integration from proteins to organs: the Physiome Project

Nat Rev Mol Cell Biol. 2003 Mar;4(3):237-43. doi: 10.1038/nrm1054.

Abstract

The Physiome Project will provide a framework for modelling the human body, using computational methods that incorporate biochemical, biophysical and anatomical information on cells, tissues and organs. The main project goals are to use computational modelling to analyse integrative biological function and to provide a system for hypothesis testing.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Computer Simulation*
  • Databases, Factual / standards*
  • Databases, Factual / trends
  • Genome
  • Human Genome Project
  • Humans
  • Models, Biological*
  • Physiological Phenomena / physiology*
  • Physiology
  • Proteome / physiology

Substances

  • Proteome