Tetrabenazine in the treatment of severe pediatric chorea

Mov Disord. 2003 Jun;18(6):703-6. doi: 10.1002/mds.10427.

Abstract

Tetrabenazine (TBZ) is widely used to treat adults with hyperkinetic movement disorders; however, published experience with the drug in pediatric patients is limited. We report on 5 children with severe chorea who were treated with TBZ. TBZ effectively controlled chorea in 4 patients, and despite the need for relatively high doses, it was well tolerated.

Publication types

  • Case Reports

MeSH terms

  • Anti-Dyskinesia Agents / therapeutic use*
  • Cerebral Palsy / drug therapy
  • Child
  • Child, Preschool
  • Chorea / drug therapy*
  • Chorea / etiology
  • Down Syndrome / complications
  • Encephalitis / complications
  • Humans
  • Infant
  • Male
  • Spasms, Infantile / complications
  • Tetrabenazine / therapeutic use*
  • Treatment Outcome

Substances

  • Anti-Dyskinesia Agents
  • Tetrabenazine