Abstract
To determine the developmental history of murine esophageal skeletal muscle, smooth muscle cells were fate mapped by lineage-specific recombination and phenotypically marked by eGFP. Examination of embryonic and postnatal tissues revealed that esophageal skeletal muscle does not arise from transdifferentiation of committed smooth muscle cells.
Copyright 2003 Wiley-Liss, Inc.
MeSH terms
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Animals
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Cell Differentiation*
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Cell Lineage*
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Esophagus / cytology
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Esophagus / embryology*
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Esophagus / growth & development*
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Green Fluorescent Proteins
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Luminescent Proteins / genetics
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Male
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Mice
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Microscopy, Fluorescence
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Muscle, Skeletal / cytology
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Muscle, Skeletal / embryology*
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Muscle, Skeletal / growth & development*
Substances
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Luminescent Proteins
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Green Fluorescent Proteins