Abstract
The methanolic extract and total alkaloids of the aerial parts of Glaucium oxylobum exhibited good activity against Microsporum gypseum, Microsporum canis, Trichophyton mentagrophytes and Epidermophyton floccosum. Four alkaloids, dicentrine, glaucine, protopine, and alpha-allocryptopine, were identified as the compounds responsible for the antifungal activity of this plant.
MeSH terms
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Alkaloids / administration & dosage
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Alkaloids / pharmacology*
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Alkaloids / therapeutic use
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Antifungal Agents / administration & dosage
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Antifungal Agents / pharmacology*
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Antifungal Agents / therapeutic use
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Dose-Response Relationship, Drug
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Humans
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Microbial Sensitivity Tests
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Mitosporic Fungi / drug effects*
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Phytotherapy*
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Plant Extracts / administration & dosage
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Plant Extracts / pharmacology*
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Plant Extracts / therapeutic use
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Plant Preparations
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Ranunculaceae*
Substances
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Alkaloids
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Antifungal Agents
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Plant Extracts
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Plant Preparations