Severe methylenetetrahydrofolate reductase deficiency, methionine synthase, and nitrous oxide--a cautionary tale

N Engl J Med. 2003 Jul 3;349(1):5-6. doi: 10.1056/NEJMp030093.
No abstract available

Publication types

  • Comment

MeSH terms

  • 5,10-Methylenetetrahydrofolate Reductase (FADH2)
  • 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase / drug effects*
  • Anesthetics, Inhalation / adverse effects*
  • Folic Acid / metabolism
  • Homocysteine / blood
  • Humans
  • Male
  • Metabolism, Inborn Errors / diagnosis*
  • Metabolism, Inborn Errors / genetics
  • Methionine / blood
  • Methylenetetrahydrofolate Reductase (NADPH2)
  • Nitrous Oxide / adverse effects*
  • Oxidoreductases / deficiency*
  • Oxidoreductases / genetics
  • Point Mutation

Substances

  • Anesthetics, Inhalation
  • Homocysteine
  • Folic Acid
  • Methionine
  • Oxidoreductases
  • 5,10-Methylenetetrahydrofolate Reductase (FADH2)
  • Methylenetetrahydrofolate Reductase (NADPH2)
  • 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase
  • Nitrous Oxide