Epidemiology and pathophysiology of ethanol-associated gastrointestinal cancer

Pharmacogenetics. 1992 Dec;2(6):278-87. doi: 10.1097/00008571-199212000-00006.

Abstract

Various epidemiological studies have given evidence on the correlation between alcohol intake and different types of cancer, especially in the upper alimentary and respiratory tract and in the liver. This review discusses the tumour stimulating effects of ethanol associated mechanisms.

Publication types

  • Review

MeSH terms

  • Animals
  • Carcinogens / toxicity
  • Epidemiologic Factors
  • Ethanol / adverse effects*
  • Gastrointestinal Neoplasms / epidemiology
  • Gastrointestinal Neoplasms / etiology*
  • Gastrointestinal Neoplasms / physiopathology
  • Humans
  • Liver Neoplasms / etiology
  • Nitrosamines / metabolism
  • Rectal Neoplasms / etiology

Substances

  • Carcinogens
  • Nitrosamines
  • Ethanol