Abstract
Cchl1a3 encodes the dihydropyridine-sensitive calcium channel alpha 1 subunit isoform predominantly expressed in skeletal muscle. mdg (muscular dysgenesis) has previously been implicated as a mutant allele of this gene. Hybridization of a rat brain cDNA probe for Cchl1a3 to Southern blots of DNAs from a panel of Chinese hamster x mouse somatic cell hybrids suggested that this gene maps to mouse Chromosome 1. Analysis of the progeny of an inbred strain cross-positioned Cchl1a3 1.3 cM proximal to the Pep-3 locus on Chr 1.
Publication types
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Research Support, U.S. Gov't, P.H.S.
MeSH terms
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Animals
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Blotting, Southern
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Calcium Channels / drug effects
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Calcium Channels / genetics*
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Chromosome Mapping*
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Cricetinae
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DNA
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DNA Probes
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Dihydropyridines / pharmacology*
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Female
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Haplotypes
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Hybrid Cells
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Mice
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Mice, Inbred BALB C
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Molecular Sequence Data
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Muscles / chemistry*
Substances
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Calcium Channels
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DNA Probes
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Dihydropyridines
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1,4-dihydropyridine
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DNA
Associated data
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GENBANK/L04150
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GENBANK/L04151
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GENBANK/L04684
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GENBANK/M88363
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GENBANK/M88364
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GENBANK/M88365
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GENBANK/M88366
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GENBANK/M90549
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GENBANK/M90550
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GENBANK/M90551