Extended spectrum beta lactamase-producing Klebsiella pneumoniae infections: a review of the literature

Archana Gupta; Krow Ampofo; David Rubenstein; Lisa Saiman

doi:10.1038/sj.jp.7210973

Extended spectrum beta lactamase-producing Klebsiella pneumoniae infections: a review of the literature

J Perinatol. 2003 Sep;23(6):439-43. doi: 10.1038/sj.jp.7210973.

Authors

Archana Gupta¹, Krow Ampofo, David Rubenstein, Lisa Saiman

Affiliation

¹ Division of Neonatology, Department of Pediatrics, The Children's Hospital of New York, New York Presbyterian Medical Center, New York, NY 10032, USA.

PMID: 13679928
DOI: 10.1038/sj.jp.7210973

Abstract

Infections caused by extended-spectrum beta-lactamase (ESBL)-producing pathogens, particularly Klebsiella pneumoniae, are increasing. The epidemiology of ESBL-producing K. pneumoniae, the mechanisms of resistance, and treatment strategies for infections caused by these organisms are reviewed.

Publication types

Review

MeSH terms

Drug Resistance, Microbial
Humans
Klebsiella Infections / enzymology
Klebsiella Infections / epidemiology
Klebsiella Infections / metabolism*
Klebsiella Infections / prevention & control
Klebsiella pneumoniae / enzymology
Klebsiella pneumoniae / metabolism*
Klebsiella pneumoniae / pathogenicity
Risk Factors
Virulence
beta-Lactamases / biosynthesis*

Substances

beta-Lactamases