Lack of asparagine depletion in the cerebrospinal fluid after one intravenous dose of PEG-asparaginase: a window study at initial diagnosis of childhood ALL

Leukemia. 2003 Nov;17(11):2254-6. doi: 10.1038/sj.leu.2403143.
No abstract available

Publication types

  • Letter

MeSH terms

  • Antineoplastic Agents / administration & dosage
  • Antineoplastic Agents / therapeutic use
  • Asparaginase / administration & dosage
  • Asparaginase / pharmacokinetics*
  • Asparaginase / therapeutic use*
  • Asparagine / cerebrospinal fluid*
  • Asparagine / deficiency
  • Child
  • Humans
  • Injections, Intravenous
  • Metabolic Clearance Rate
  • Polyethylene Glycols / administration & dosage
  • Polyethylene Glycols / pharmacokinetics*
  • Polyethylene Glycols / therapeutic use*
  • Precursor Cell Lymphoblastic Leukemia-Lymphoma / cerebrospinal fluid*
  • Precursor Cell Lymphoblastic Leukemia-Lymphoma / drug therapy*
  • Time Factors

Substances

  • Antineoplastic Agents
  • Polyethylene Glycols
  • Asparagine
  • pegaspargase
  • Asparaginase