DnaSP, DNA polymorphism analyses by the coalescent and other methods

Julio Rozas; Juan C Sánchez-DelBarrio; Xavier Messeguer; Ricardo Rozas

doi:10.1093/bioinformatics/btg359

DnaSP, DNA polymorphism analyses by the coalescent and other methods

Bioinformatics. 2003 Dec 12;19(18):2496-7. doi: 10.1093/bioinformatics/btg359.

Authors

Julio Rozas¹, Juan C Sánchez-DelBarrio, Xavier Messeguer, Ricardo Rozas

Affiliation

¹ Departament de Genètica, Facultat de Biologia, Universitat de Barcelona, Diagonal 645, 08071 Barcelona, Spain. jrozas@ub.edu.es

PMID: 14668244
DOI: 10.1093/bioinformatics/btg359

Abstract

Summary: DnaSP is a software package for the analysis of DNA polymorphism data. Present version introduces several new modules and features which, among other options allow: (1) handling big data sets (approximately 5 Mb per sequence); (2) conducting a large number of coalescent-based tests by Monte Carlo computer simulations; (3) extensive analyses of the genetic differentiation and gene flow among populations; (4) analysing the evolutionary pattern of preferred and unpreferred codons; (5) generating graphical outputs for an easy visualization of results.

Availability: The software package, including complete documentation and examples, is freely available to academic users from: http://www.ub.es/dnasp

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Algorithms*
Gene Expression Profiling / methods*
Polymorphism, Genetic / genetics*
Sequence Alignment / methods
Sequence Analysis, DNA / methods*
Software*
User-Computer Interface*