Abstract
A case of arsenical keratosis with multiple lesions of Bowen's disease and squamous cell carcinoma is described. The patient was successfully treated with a combination of acitretin and intralesional 5-fluorouracil. All the lesions resolved after three months of therapy with no side effects and no recurrence during four months of follow-up.
MeSH terms
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Acitretin / administration & dosage*
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Arsenic / adverse effects*
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Biopsy, Needle
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Bowen's Disease / complications
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Bowen's Disease / drug therapy*
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Bowen's Disease / pathology
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Carcinoma, Squamous Cell / complications
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Carcinoma, Squamous Cell / drug therapy
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Carcinoma, Squamous Cell / pathology
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Drug Therapy, Combination
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Fluorouracil / administration & dosage*
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Follow-Up Studies
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Humans
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Immunohistochemistry
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India
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Injections, Intralesional
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Keratosis / chemically induced
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Keratosis / complications
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Keratosis / drug therapy*
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Keratosis / pathology
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Male
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Middle Aged
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Precancerous Conditions / chemically induced
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Precancerous Conditions / drug therapy
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Precancerous Conditions / pathology
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Skin Neoplasms / complications
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Skin Neoplasms / drug therapy*
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Skin Neoplasms / pathology
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Treatment Outcome
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Water Pollutants / adverse effects
Substances
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Water Pollutants
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Acitretin
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Arsenic
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Fluorouracil