Abstract
IGF-1 and growth hormone (GH) interact with insulin to modulate its control of carbohydrate metabolism. A new study (see the related article beginning on page 96) shows that blocking the effect of GH in the presence of low serum IGF-1 concentrations enhances insulin sensitivity.
MeSH terms
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Animals
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Growth Hormone / pharmacology
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Growth Hormone / physiology
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Human Growth Hormone / physiology*
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Insulin / pharmacology*
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Insulin / physiology*
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Insulin-Like Growth Factor I / deficiency
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Insulin-Like Growth Factor I / physiology*
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Mice
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Mice, Knockout
Substances
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Insulin
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Human Growth Hormone
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Insulin-Like Growth Factor I
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Growth Hormone