Development of a depressed left ventricular ejection fraction in patients with left ventricular hypertrophy and a normal ejection fraction

J Eduardo Rame; Marlon Ramilo; Nali Spencer; Christopher Blewett; Sameer K Mehta; Daniel L Dries; Mark H Drazner

doi:10.1016/j.amjcard.2003.09.050

Development of a depressed left ventricular ejection fraction in patients with left ventricular hypertrophy and a normal ejection fraction

Am J Cardiol. 2004 Jan 15;93(2):234-7. doi: 10.1016/j.amjcard.2003.09.050.

Authors

J Eduardo Rame¹, Marlon Ramilo, Nali Spencer, Christopher Blewett, Sameer K Mehta, Daniel L Dries, Mark H Drazner

Affiliation

¹ Cardiovascular Branch, National Heart, Lung, and Blood Institute, Bethesda, Maryland, USA.

PMID: 14715358
DOI: 10.1016/j.amjcard.2003.09.050

Abstract

The progression from concentric left ventricular (LV) hypertrophy to heart failure has not been well defined. Of 159 predominantly hypertensive African-American patients with LV hypertrophy and a normal ejection fraction (EF), 28 (18%) developed a reduced EF after a median follow-up of approximately 4 years. Risk factors for this outcome included a history of coronary artery disease, pulmonary edema seen on a chest x-ray, or a subsequent myocardial infarction.

MeSH terms

Black or African American
Coronary Disease / epidemiology
Disease Progression
Echocardiography
Female
Follow-Up Studies
Heart Failure / epidemiology
Humans
Hypertension / epidemiology
Hypertension / physiopathology*
Hypertrophy, Left Ventricular / diagnostic imaging*
Logistic Models
Male
Middle Aged
Myocardial Infarction / epidemiology
Pulmonary Edema / epidemiology
Retrospective Studies
Risk Factors
Stroke Volume / physiology*
Time Factors
Ventricular Dysfunction, Left / diagnostic imaging*