Teratological studies of prenatal exposure of mice to a 20 kHz sawtooth magnetic field

Bioelectromagnetics. 2004 Feb;25(2):114-7. doi: 10.1002/bem.10164.

Abstract

In order to evaluate the importance of gestational age in possible effects due to exposure to a 20 kHz sawtooth magnetic field, pregnant ICR mice at gestational 2.5-15.5 days post-coitus, which is the most sensitive stage for the induction of major congenital malformations, were exposed in a carrousel irradiator. The mice were exposed to a 20 kHz intermediate frequency (IF) sawtooth magnetic field had a 6.5 microT peak intensity for 8 h/day. The animals were sacrificed on the 18th day of gestation; and the fetuses were examined for mortality, growth retardation, changes in head size, and other morphological abnormalities. From the above conditions, it is concluded that the exposure to a 20 kHz sawtooth magnetic field with 6.5 microT peak intensity does not inflict any adverse effect on fetuses of pregnant mice.

MeSH terms

  • Abnormalities, Radiation-Induced / etiology*
  • Animals
  • Dose-Response Relationship, Radiation
  • Electromagnetic Fields*
  • Female
  • Fetal Death / etiology*
  • Fetal Growth Retardation / etiology*
  • Fetal Weight / radiation effects*
  • Fetus / radiation effects*
  • Mice
  • Mice, Inbred ICR
  • Pregnancy
  • Prenatal Exposure Delayed Effects
  • Radiation Dosage
  • Survival Analysis