A unique, single-blind, controlled trial of egg exclusion was performed in infants under 3 years of age, with atopic dermatitis, and/or their breast-feeding mothers. All subjects were put on an exclusion diet, but assessment of the effect of egg exclusion was made without knowing the results of allergy the tests. Results showed that there was a statistically significant correlation between the effect of egg exclusion and egg allergy, but only in infants 3-6 months old. Combination with other allergies did not seem to affect the results at this age. These findings indicate that egg exclusion is effective in ameliorating skin symptoms of atopic dermatitis only in early infancy and in the presence of egg allergy, irrespective of combination with other food allergies. This may be correlated to high RAST scores to egg at this age.