Aging and wound healing

World J Surg. 2004 Mar;28(3):321-6. doi: 10.1007/s00268-003-7397-6. Epub 2004 Feb 17.

Abstract

Impaired wound healing in the elderly presents a major clinical and economic problem. With the aging population growing in both number and percentage, the importance of understanding the mechanisms underlying age-related impairments in healing is increased. Normal skin exhibits characteristic changes with age that have implications for wound healing. Additionally, the process of wound healing is altered in aged individuals. Although historically healing in the aged was considered defective, there is now consensus that healing in the elderly is delayed but the final result is qualitatively similar to that in young subjects.

Publication types

  • Research Support, U.S. Gov't, P.H.S.
  • Review

MeSH terms

  • Aged
  • Aged, 80 and over
  • Aging / physiology*
  • Female
  • Growth Substances / metabolism
  • Humans
  • Male
  • Prognosis
  • Regeneration / physiology
  • Risk Assessment
  • Skin Aging / physiology
  • Skin Physiological Phenomena*
  • Wound Healing / physiology*

Substances

  • Growth Substances