Catalytic, highly enantio, and diastereoselective nitroso diels-alder reaction

Yuhei Yamamoto; Hisashi Yamamoto

doi:10.1021/ja049849w

Catalytic, highly enantio, and diastereoselective nitroso diels-alder reaction

J Am Chem Soc. 2004 Apr 7;126(13):4128-9. doi: 10.1021/ja049849w.

Authors

Yuhei Yamamoto¹, Hisashi Yamamoto

Affiliation

¹ Department of Chemistry, The University of Chicago, Illinois, USA. yamamoto@uchicago.edu

PMID: 15053601
DOI: 10.1021/ja049849w

Abstract

This communication presents studies that nitroso Diels-Alder adduct has been furnished in uniformly high yield and high enantioselectivity using nitrosopyridine as a substrate and copper as a catalyst. The obtained Diels-Alder adduct was easily transformed to corresponding chiral amino alcohols without loss of enantioselectivity.