Epidemic resurgence of Chikungunya virus in democratic Republic of the Congo: identification of a new central African strain

J Med Virol. 2004 Oct;74(2):277-82. doi: 10.1002/jmv.20168.

Abstract

The resurgence of Chikungunya virus is described during an urban epidemic in Kinshasa Democratic Republic of the Congo, after 39 years without any isolation of the virus. Chikungunya virus was isolated in sera from nine patients with clinical symptoms. A 1,200 bp long partial sequence of the E1/3'UTR genomic region was determined for each isolate. All sequences clustered in the central African lineage. They constitute Chikungunya virus reference sequences for the Democratic Republic of the Congo.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Alphavirus Infections / epidemiology*
  • Alphavirus Infections / virology
  • Antibodies, Viral / blood
  • Chikungunya virus / classification
  • Chikungunya virus / genetics
  • Chikungunya virus / immunology
  • Chikungunya virus / isolation & purification
  • Communicable Diseases, Emerging / epidemiology*
  • Communicable Diseases, Emerging / virology
  • Democratic Republic of the Congo / epidemiology
  • Disease Outbreaks*
  • Humans
  • Malaria, Falciparum / complications
  • Molecular Epidemiology
  • Molecular Sequence Data
  • Phylogeny
  • Sequence Analysis, DNA

Substances

  • Antibodies, Viral

Associated data

  • GENBANK/AY549575
  • GENBANK/AY549576
  • GENBANK/AY549577
  • GENBANK/AY549578
  • GENBANK/AY549579
  • GENBANK/AY549580
  • GENBANK/AY549581
  • GENBANK/AY549582
  • GENBANK/AY549583
  • GENBANK/AY549584