Glutamic protease distribution is limited to filamentous fungi

FEMS Microbiol Lett. 2004 Oct 1;239(1):95-101. doi: 10.1016/j.femsle.2004.08.023.

Abstract

Glutamic proteases are a distinct, and recently re-classified, group of peptidases that are thought to be found only in fungi. We have identified and analysed the distribution of over 20 putative glutamic proteases from all fungal species whose genomes have been sequenced so far. Although absent from the Saccharomycetales class, glutamic proteases appear to be present in all other ascomycetes species examined. A large number of coding regions for glutamic proteases were also found clustered together in the Phanerochaete chrysosporium genome, despite apparently being absent from three other species of Basidiomycota.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Fungi / enzymology*
  • Fungi / genetics
  • Genome, Fungal*
  • Genomics*
  • Glutamic Acid / metabolism*
  • Peptide Hydrolases / genetics
  • Peptide Hydrolases / metabolism*
  • Phanerochaete / enzymology
  • Phanerochaete / genetics

Substances

  • Glutamic Acid
  • Peptide Hydrolases