Clinical efficacy of magnesium supplementation in patients with type 2 diabetes

J Am Coll Nutr. 2004 Oct;23(5):506S-509S. doi: 10.1080/07315724.2004.10719390.

Abstract

Effects of magnesium (Mg) supplementation on nine mild type 2 diabetic patients with stable glycemic control were investigated. Water from a salt lake with a high natural Mg content (7.1%) (MAG21) was used for supplementation after dilution with distilled water to 100mg/100mL; 300mL/day was given for 30 days. Fasting serum immunoreactive insulin level decreased significantly, as did HOMA squareR (both p < 0.05). There was also a marked decrease of the mean triglyceride level after supplementation. The patients with hypertension showed significant reduction of systolic (p < 0.01), diastolic (p = 0.0038), and mean (p < 0.01) blood pressure. The salt lake water supplement, MAG21, exerted clinical benefit as a Mg supplement in patients with mild type 2 diabetes mellitus.

MeSH terms

  • Blood Glucose / analysis*
  • Blood Pressure / drug effects
  • Diabetes Mellitus, Type 2 / blood
  • Diabetes Mellitus, Type 2 / drug therapy*
  • Dietary Supplements
  • Fasting
  • Female
  • Humans
  • Hypoglycemic Agents / administration & dosage
  • Hypoglycemic Agents / therapeutic use*
  • Insulin / blood
  • Magnesium / administration & dosage
  • Magnesium / therapeutic use*
  • Male
  • Middle Aged
  • Treatment Outcome
  • Triglycerides / blood
  • Water

Substances

  • Blood Glucose
  • Hypoglycemic Agents
  • Insulin
  • Triglycerides
  • Water
  • Magnesium