Matrix metalloproteinases: their function in tissue repair

J Wound Care. 2005 Jan;14(1):20-2. doi: 10.12968/jowc.2005.14.1.26720.

Abstract

Matrix metalloproteinases are involved in all stages of cutaneous wound repair and play a key role in regulating the balance between tissue synthesis and tissue destruction. Greater understanding of this may result in better treatment options.

Publication types

  • Review

MeSH terms

  • Acute Disease
  • Anti-Inflammatory Agents / therapeutic use
  • Cell Movement / physiology
  • Cell Proliferation
  • Chronic Disease
  • Extracellular Matrix / physiology
  • Fibroblasts / physiology
  • Growth Substances / therapeutic use
  • Humans
  • Inflammation
  • Matrix Metalloproteinase Inhibitors
  • Matrix Metalloproteinases / physiology*
  • Neovascularization, Physiologic / physiology
  • Protease Inhibitors / therapeutic use
  • Skin Physiological Phenomena / immunology
  • Wound Healing / physiology*
  • Wounds and Injuries / immunology
  • Wounds and Injuries / physiopathology*
  • Wounds and Injuries / therapy

Substances

  • Anti-Inflammatory Agents
  • Growth Substances
  • Matrix Metalloproteinase Inhibitors
  • Protease Inhibitors
  • Matrix Metalloproteinases